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OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide

Hugo Sepulveda, Xiang Li, Xiaojing Yue, et al.

Scalable and efficient generation of mouse primordial germ cell-like cells

Xinbao Ding, Liangdao Li, Jingyi Gao, et al.

Mitochondrial citrate carrier SLC25A1 is a dosage-dependent regulator of metabolic reprogramming and morphogenesis in the developing heart

Chiemela Ohanele, Jessica N. Peoples, Anja Karlstaedt, et al.

Comparative developmental genomics of sex-biased gene expression in early embryogenesis across mammals

Victorya Richardson, Kai Zhang, Nora Engel, et al.

Developmentally programmed epigenome regulates cellular plasticity at the parental-to-zygote transition

Ryan J. Gleason, Christopher S. Semancik, Gitanjali Lakshminarayanan, et al.

Diverse mechanisms for epigenetic imprinting in mammals

Daniel Andergassen, Zachary D. Smith, John L. Rinn, et al.

Toll-like receptor 4 is activated by platinum and contributes to cisplatin-induced ototoxicity

Ghazal Babolmorad, Asna Latif, Niall M. Pollock, et al.

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Application of the in vivo oxidative stress reporter Hmox1 as mechanistic biomarker of arsenic toxicity

Francisco Inesta-Vaquera, Panida Navasumrit, Colin J. Henderson, et al.

Primate naïve pluripotent stem cells stall in the G1 phase of the cell cycle and differentiate prematurely during embryo colonization

Irène Aksoy, Cloé Rognard, Anaïs Moulin, et al.

Astrocytes and neurons share brain region-specific transcriptional signatures

Álvaro Herrero-Navarro, Lorenzo Puche-Aroca, Verónica Moreno-Juan, et al.

Cross-species transcriptomic and epigenomic analysis reveals key regulators of injury response and neuronal regeneration in vertebrate retinas

Thanh Hoang, Jie Wang, Patrick Boyd, et al.

Dynamic Erasure of Random X-Chromosome Inactivation during iPSC reprogramming

Adrian Janiszewski, Irene Talon, Juan Song, et al.

STAT3 promotes melanoma metastasis by CEBP-induced repression of the MITF pigmentation pathway

Alexander Swoboda, Robert Soukup, Katharina Kinslechner, et al.